In the near future the world is a dark dystopian place with massive inequality and huge corporations effectively running things.
Information technology has become ubiquitous with people inhabiting cyberspace but also infusing their bodies with technology. Corporate wars and infighting are everywhere and the line between organised crime and business is very grey. Some fight back against oppression in the real world others in cyberspace.
Living on the fringes of the corporate world is Johnny (Keanu Reeves) who transports data for money, uploaded into his mind through an implant. His latest job goes badly wrong after he overloads his mind with stolen data just as vengeful Yakuza turn up to take it, killing his customers in the process.
Escaping, he heads to the drop-off hoping to offload the data, pursued by the Yakuza who want to remove it from his head slightly more forcefully. When he arrives he falls in with local bodyguard for hire Jane (Dina Meyer) who says she knows a guy who can help.