It is a focus group test event for Antenna Research's new game, eXistenZ by famed designer Allegra Geller (Jennifer Jason Leigh). Play is conducted by 'porting in' to fleshy 'game pods'.
Security is tight, but just as play is about to begin, an audience member shouts "Death to the Demoness Allegra Gellar" as he shoots her with a grotesque biomechanical pistol, wounding her. The guards shoot the assassin and Gellar flees with marketing intern Ted Pikul (Jude Law), who grabs the strange weapon.
Paranoid that this may have been an inside job, the reclusive Gellar makes Ted discard his phone and the pair go into hiding. Once safe she is concerned that the one and only copy of this multi-million dollar five year development project may have been damaged and persuades Ted the only way to tell is to play it with somebody friendly. However, Ted Pikul has never played one of the company's games before and to do so requires implanted hardware.
No good will come of this.
CW: Cronenberg delivers gruesome biomechanical/mutant visuals, often in a slaughterhouse style. Also eating repulsive stuff and things like pulling out your own teeth. Not in a horror movie torture way but a completely casual manner like it's just something that happens.